Bioterrorism Specialists – Plague Lesson 3.


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Bioterrorism Specialists – Plague Lesson 3 Differential Finding Goals List the infections that ought to be considered in the differential analysis of maladie Depict how to preclude different sicknesses when diagnosing plague Bubonic Disease Brooding: 2 to 6 days Manifestations Chills, high fever
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Bioterrorism Agents – Plague Lesson 3 Differential Diagnosis

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Objectives List the ailments that ought to be considered in the differential determination of maladie Describe how to preclude different ailments when diagnosing sickness

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Bubonic Plague Incubation: 2 to 6 days Symptoms Chills, high fever Swollen and excruciating lymph hubs in crotch, thigh, underarm and/or neck Buboes at site of immunization Lymph hubs not hot, skin smooth and red Rapid heartbeat Hypotension

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Bubonic Plague Disease Progression Septicemia Pneumonic Plague Meningitis (uncommon) Other Symptoms Restlessness, disarray, absence of coordination Intestinal distress Lymph hubs may suppurate second week

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Bubonic Plague Differential Diagnosis Capnocytophaga canimorsus Cellulitis Lymphogranuloma venereum Non-particular contaminations Lymphogranuloma venereum

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Bubonic Plague Differential Diagnosis © 2003 CIDRAP/IDSA

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Bubonic Plague Differential Diagnosis © 2003 CIDRAP/IDSA

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Bubonic Plague Differential Diagnosis © 2003 CIDRAP/IDSA

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Pneumonic Plague Incubation: 2 to 4 days (Range: 1-6 days) Symptoms Fever, chills, discomfort, myalgias Productive hack, watery mucoid Chest agony, dyspnea Hemoptysis Gastrointestinal Cervical Bubo (uncommon)

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Pneumonic Plague Rapidly dynamic Respiratory disappointment inside of 2 to 4 days Chest X-Rays – two-sided sketchy penetrates Shock, hypotension, multi-organ disappointment Treat inside of 24 hours or generally deadly

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Pneumonic Plague

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Primary Pneumonic Plague Outbreak Diagnoses Presumptive; particularly if related Rule out different reasons Severe pneumonia Rapidly dynamic respiratory contamination With or without sepsis

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Primary Pneumonic Plague Differential Diagnosis Inhalational Bacillus anthracis Tularemia Community-obtained bacterial pneumonia Viral pneumonia Q fever Anthrax

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Primary Pneumonic Plague Differential Diagnosis © 2003 CIDRAP/IDSA

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Primary Pneumonic Plague Differential Diagnosis © 2003 CIDRAP/IDSA

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Primary Pneumonic Plague Differential Diagnosis © 2003 CIDRAP/IDSA

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Septicemic Plague Incubation: Most regular as inconvenience Symptoms Fever, chills, surrender Gastrointestinal Disease Progression Pupura DIC Amputation Pupura

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Septicemic Plague Differential Diagnosis © 2003 CIDRAP/IDSA

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Review Questions Plague Lesson 3

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Plague Review Question Lesson 3, Question 1 36yo, F, Chicago, IL Housekeeper No hx of travel, creature presentation Symptoms Severe stomach torment Productive hack Shortness of breath

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Plague Review Question Lesson 3, Question 1 Exam Findings Productive hack, thick, bleeding sputum Bilateral rales Little-to-no air development lower left lung field Chest X-Ray – reciprocal invades CSF – Cloudy Temperature – 102.3  F Pulse fast and thready Liver not amplified, no extended lymph hubs What conclusions would you discount?

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Plague Review Question Lesson 3, Question 1 What determinations would you preclude? Bacillus anthracis Tularemia Pneumonic Plague Bubonic Plague

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Plague Review Question Lesson 3, Question 1 What conclusions would you discount? C. Pneumonic Plague

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Plague Review Question Lesson 3, Question 2 32yo, M, Philadelphia, PA Computer Programmer No hx travel, Healthy canine Symptoms Headache, chills, fever x 2 days Vomiting x 1 day Orange-sized swelling, left inguinal Delirious What ailments would you incorporate in differential?

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Plague Review Question Lesson 3, Question 2 What diseases would you incorporate in differential? Tularemia Chancroid Cat-Scratch Fever Bubonic Plague

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Plague Review Question Lesson 3, Question 2 What sicknesses would you incorporate in differential? D. Bubonic Plague

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Plague Review Question Lesson 3, Question 3 56yo, M, Miami, Florida Salesman Hx of Travel to New Mexico a week ago No hx of creature introduction Symptoms Malaise, myalgia, chills, migraine, GI sxs x 3 days Worsening sx’s, serious stomach, profitable hack, shortness of breath x 1 day Today – Pupura, DIC, hypotension How might you relate it to torment?

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Plague Review Question Lesson 3, Question 3 How might you relate it to torment? Vicinity of gram-positive microscopic organisms Hx of go to torment endemic range Rapid movement of ailment B and C

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Plague Review Question Lesson 3, Question 3 How might you relate it to torment? Both B and C Hx of go to torment endemic range Rapid movement of

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