Contextual investigation Pathogenic Bacteriology 2009 .

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Case Study Pathogenic Bacteriology 2009. Case #7, 34, 64 Evelyn Loi Hien Dang Jose Cervantes Jr. Case Summary. 8:00am 65-year-old woman bitten by her cat on dorsal aspect of the right middle finger. 4:00pm swelling and pain the finger and dorsum of the right hand.
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Contextual investigation Pathogenic Bacteriology 2009 Case #7, 34, 64 Evelyn Loi Hien Dang Jose Cervantes Jr.

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Case Summary 8:00am 65-year-old lady nibbled by her feline on dorsal part of the right center finger. 4:00pm swelling and torment the finger and dorsum of the right hand. torment in the axilla, red streaking up the lower arm, and chills. Body temperature: 38 o C Lab Aspiration of sore sent for culture Operating room Incision and seepage of sore

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Key Information Pointing to Diagnosis Age Body temperature 38 o C Arm Red streaking Pain in axilla Hand Erythema Swelling Warmth Tenderness of finger Elevated WBC 12,000/microliter

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Classification,Gram Stain Results, and Microscopic Appearance of Pathogen 1. Which life form was disengaged on culture of the canker? Family: Pasteurellacaea Genus: Pasteurella Species: multocida Gram – Coccobacilli Bipolar recoloring Fermentative Non-motile Facultative anaerobe

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Diagnosis/Isolation/Identification/of Pathogen Media No development on Mac plate Growth on Chocolate and Blood Agar Biochemical testing Oxidase + Indole + Catalase+ Nitrate + Urease -

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Diseases and Pathogenesis of Disease Caused by P. multocida Virulence Factor Endotoxin Capsule What is the repository of this living being? How do people most generally get to be contaminated by this living being? Upper respiratory tract of pets and ranch creatures as NF Bites or scratches exacted by mutts and felines

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Diseases brought about by Pasteurella Soft tissue aggravation Purulent injuries, cellulitis, abscesses Deep delicate tissue irritation Tenosynovitis Septic joint pain Osteomyelitis Which other clinical disorders can be brought about by this life form? Systemic contamination (uncommon) Endocarditis Meningitis Eyes Conjunctivitis Corneal ulcer Respiratory Pharangitis Pneumonia (patients with fundamental aspiratory malady)

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Therapy and Prognosis of Patient Infected with P. multocida Cat chomps are more awful than puppy nibbles in view of their little, sharp and penetrative teeth. Forceful living being Symptoms show up inside 24 hours Sensitive to anti-infection agents Antibiotics Highly touchy to Penicillin Chloramphenicol Tetracyclin Ciprofloxins

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How can contamination with this life form be averted? Youthful newborn children ought to dodge contact with the salivation of pooches and felines Inform immunocompromised patients and youngsters about Pasteurella disease and creature introduction Don\'t pet odd creatures Never trouble a creature that is eating or resting Be certain family unit pets are a la mode on their immunizations Seek restorative counsel if there is redness, swelling, or agony in the event that you endure a creature chomp.

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Primary Research Article Contributing to the Understanding of the Disease brought about by Pasteurella multocida Freshwater, A. (2008). Why Your Housecat\'s Trite Little Bite Could Cause You Quite a Fright: A Study of Domestic Felines on the Occurrence and Antibiotic Susceptibility of Pasteurella multocida. Zoonoses and Public Health. 55:507-513. Reason Identify potential anti-toxin resistance Examine carriage rate Materials and Methods Specimen gathering 409 veterinary centers, empathetic safe houses, private home Cats\' gingival edges Culture and ID of examples CBA, MacConkey Antibiotic powerlessness testing Penicillin and Penicillin subsidiaries G-tests Age, breed, sustenance sort, gingival scale, way of life and sex

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Results & Discussion G test No huge relationship between individual components and the nearness of P. multocida Carriage rate is 90% Susceptibility testing (Penicillin subsidiaries) is still the reasonable technique to treat feline chomp wounds Canine nibbles far dwarf feline chomps 20-80% of all feline chomp wounds get to be contaminated 3-18% of pooch nibble wounds get to be tainted Table 1 % Susceptibility in 409 secludes of Pasteurella multocida Table 2 Characterization of Pasteurella multocida

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Take Home Message Pasteurella multocida Diseases for the most part includes residential creatures, for example, felines and puppies Typical manifestations boil and cellulitis at neighborhood wounds Fever Elevated white platelets Diagnostics Antimicrobial weakness testing Pasteurella can be forceful (side effects inside 24 hours) be that as it may it can be dealt with effortlessly. Penicillin Prevention Inform kids and immunocompromised people about Pasteurella contamination and creature introduction. Transmission creature nibble, scratches, licks, and inward breath

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References Freshwater, A. (2008). Why Your Housecat\'s Trite Little Bite Could Cause You Quite a Fright: A Study of Domestic Felines on the Occurrence and Antibiotic Susceptibility of Pasteurella multocida . Zoonoses and Public Health. 55:507-513. Bryant, Barbara J. et al. (2007). Pasteurella multocida bacteremia in asymptomatic plateletpheresis contributors: a story of two felines. Transfusion. 47: 1984-1989. Green, Bryant T. et al. (2001). Pasteurella multocida Meningitis: Case Review of the last 11 Y. Scand J Infect Dis. 34:213-217 Loiez, Caroline et al. (2002). Pasteurella multocida and Intrauterine Device: A Woman and her Pets. Scand J Infect Dis. 34:473-474 Wade, T. et al. (1999). Pasteurella multocida meningitis in earliest stages (a lick might be as awful as a nibble). Eur J Pediatr 158: 875-878 Kimura, Ryosuke et al. (2004) Pasteurella multocida septicemia created by close contact with a residential feline: case report and writing survey. J Infect Chemoter. 10: 250-252 McQueen, Nancy. Winter 2009. Pasteurellacaea.

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