Dr. Hasan Ali Nogay M.D. Submerged and HYPERBARIC MEDICINE SPECIALIST MEDICAL ESTHETICIAN MESOTHERAPIST .


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2. . HISTORY OF MESOTHERAPY . 1952 : Dr PISTOR PERFORMS AN INTRAVENOUS INJECTION OF 10 ml OF PROCAINE TO AN ASTHMATIC PERSON.HIS SHORTNESS OF BREATH DOES NOT IMPROVE, BUT HIS DEAFNESS DECREASED.Dr PISTOR THEN HAS THE SIMPLE BUT BRILLIANT IDEA OF INJECTING SMALL DOSES OF PROCAIN FROM 3 TO 5 MM DEEP AROUND THE PATIENT\'S EAR.THIS THERAPY PROVES TO BE MORE EFFICIENT THAN WHEN GIVEN SYSTEMICALLY..
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Dr . Hasan Ali Nogay M.D. Submerged and HYPERBARIC MEDICINE SPECIALIST MEDICAL ESTHETICIAN MESOTHERAPIST ADDRESS : Demircikara mh. Avni Tolnay Cad. No:46/1, Narenciye Antalya-TÜRKİYE TEL. : +9 0 .242 . 322.00.99 e-mai l : www.drnogay.com

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HISTORY OF MESOTHERAPY 1952 : Dr PISTOR PERFORMS AN INTRAVENOUS INJECTION OF 10 ml OF PROCAINE TO AN ASTHMATIC PERSON. HIS SHORTNESS OF BREATH DOES NOT IMPROVE, BUT HIS DEAFNESS DECREASED. Dr PISTOR THEN HAS THE SIMPLE BUT BRILLIANT IDEA OF INJECTING SMALL DOSES OF PROCAIN FROM 3 TO 5 MM DEEP AROUND THE PATIENT\'S EAR. THIS THERAPY PROVES TO BE MORE EFFICIENT THAN WHEN GIVEN SYSTEMICALLY.

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HISTORY OF MESOTHERAPY 1958 THE NAME MESOTHERAPY IS SUGGESTED IN THE FRENCH MEDICAL PRESS. FOR Dr PISTOR, HIS TREATMENT MODALITY SEEMED ACTIVE ON THE MESODERM AND ITS DERIVATES ; THEREFORE THE TERM "MESO" . 1976 CONSULTATIONS OF MESOTHERAPY ARE PERFORMEDBY Dr DALLOZ-BOURGUIGNON IN NECKER\'S HOSPITAL (PARIS). 1981 FIRST MESOTHERAPY CONSULTATION FOR PROFESSIONAL ATHLETES (INSTIITUT NATIONAL DES SPORTS DE PARIS) Y. DEMARAIS\'SERVICE , PERFORMED BY Dr. J. LE COZ.

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HISTORY OF MESOTHERAPY 1982 FIRST UNIVERSITY DIPLOMA IN MESOTHERAPY AT THE FACULTY OF MEDICINE OF PARIS XIII (Dr. M. BICHERON). 1987 MESOTHERAPY IS OFFICIALLY RECOGNIZED AS PART OF TRADITIONAL MEDICINE. 1991 CREATION OF SOCIETE FRANCAISE DE MESOTHERAPIE (1600 MEMBERS). 2002 MESOTHERAPY IS TAUGHT AT THE FACULTY OF MEDICINE IN MARSEILLE, BORDEAUX, PARIS. FRENCH HEALTH SYSTEM RECOGNIZES THE MESOTHERAPY ACT .

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HISTORY OF MESOTHERAPY 2003 DEATH OF Dr MICHEL PISTOR WHO WAS A PASSIONATE INVENTOR, A POET AND A HUMANIST, DURING HIS WHOLE LIFE. 2004 IN FRANCE, APPROXIMATELY 15 000 DOCTORS USE MESOTHERAPY DAILY AND UP TO 60 000 PERSONS ARE TREATED BY MESOTHERAPY EVERY DAY.

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DEFINITIONS OF MESOTHERAPY DR PISTOR QUOTE : « A LITTLE, RARELY, IN THE RIGHT SPOT » IS STILL TRUE . A LITTLE : IN MESOTHERAPY, SMALL DOSES OF DRUGS ARE ADMINIST E RED. MESOTHERAPY GIVES THE OPPORTUNITY OFCOMBINING BETWEEN TWO TO FIVE DRUGS WITH A SIMPLE INJECTION. Once in a while : INITIALLY, MESOTHERAPY SHOULD NOT BE PERFORMED MORE THAN ONCE A WEEK (FROM 2 TO 6 SESSIONS) . AFTER, THE OTHER SESSIONS CAN BE DONE EVERY FIFTEEN DAYS AND "UP KEEP" SESSIONS EVERY MONTH. IN THE RIGHT SPOT : MESOTHERAPY IS PRACTICED WITH INJECTIONS AT THE SITE OF PAIN OR PATHOLOGY

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DEFINITIONS OF MESOTHERAPY IS A MEDICAL TECHNIQUE IT CONSISTS OF DERMO-EPIDERMIC INJECTIONS ( 1 TO 13 MM DEEP ) USUALLY OF ALLOPATHIC PRODUCTS VARYING WITH THE PATHOLOGY TO BE TREATED. WITH SMALL DOSES OF DRUGS, WE OBTAIN AN EFFECTIVE MAXIMALE CONCENTRATION. THE SYSTEMIC, GASTRIC AND HEPATIC PASSAGE IS MINIMAL WHICH RESULTS IN ALMOST ABSOLUTE SAFETY.

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MESOTHERAPY GENERALITIES MESOTHERAPY IS A TREATMENT STIMULATING THE MESODERM OR MIDDLE LAYER OF THE SKIN. CONCERNING Esthetic MEDICINE : CELLULITE WEIGHT LOSS BODY SCULPTING HAIR LOSS FACE AND NECK REJUVENATION MESOTHERAPY INVOLVES : THE INJECTION OF A CUSTOMIZED MIXTURE WITH EXTREMELY SMALL NEEDLES (GENERALLY 4 TO 6 MM). Only A DROP OF THE SOLUTION : IS PLACED AT EACH INJECTION SITE. Just INTO THE PROBLEMATIC AREA. THE PROCEDURE : IS REALY PAINLESS REQUIRES NO PREPARATION OR RECOVERY TIME, NO BANDAGES, NO INTERRUPTION OF THE DAILY LIFE. Symptoms : GENERALLY LIMITED TO BRUISING (WHEN DHD TECHNIQUE IS USED WITH A DEPTH OF 10 MM). IT IS A SAFE TREATMENT, WHEN PERFORMED BY AN EXPERIENCED CLINICIAN. React WELL TO MESOTHERAPY

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DIFFERENT TECHNIQUES OF INJECTION EPIDERMIC MESOTHERAPY DERIVATE OF MULTIPRICKING NO BLEEDING THE EDGE OF THE NEEDLE DIRECTED UPWARD MOVEMENT BACKWARD AND FOWARD MOTION IN THE Ax OF THE NEEDLE "NAPPAGE" : MULTI-PRICKING A THIRD OF THE CONTENTS OF THE SYRINGE IS INJECTED THE REST IS LOST PAPULA " POINT BY POINT " WE PRICK, WE INJECT, WE REMOVE THE NEEDLE

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TERMINOLOGY RESULTING FROM CONSENSUS OF SCIENTIFIC COMITEE OF SOCIETE FRANCAISE DE MESOTHERAPIE (S.F.M.) IED : INTRAEPIDERMIC INJECTION : 1 MM ID : INTRADERMIC INJECTION : 1 to 4 MM OF DEPTH IDS : SUPERFICIAL INTRADERMIC: 1 to 2 MM (NAPPAGE) IDP : DE E P INTRADERMIC INJECTION : 3 to 4 MM DHP : DERMO HYPODERMIC : 2 to 10 MM PPP : POINT BY POINT : 2 to 4 MM

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MESOTHERAPY TECHNIQUE NO AGGRESSIVE INJECTION. NO INJECTION DEEPER THAN 10 MM. NO MIXTURE CONTAINING MORE THAN 4 OR 5 DRUGS. A LITTLE, RARELY, IN THE RIGHT SPOT. MATERIAL USED ONLY ONCE. Purification OF THE INJECTED AREA WITH CHLORHEXIDINE OR BENZYLIC ALCOHOL. WEARING GLOVES IS RECOMMENDED. A GOOD SESSION MUST BE PAINLESS AND LEAVE MINIMAL OR NO MARKS AT ALL.

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MATERIAL USE MULTI-INJECTORS AND MULTI-PUNCTURE HAVE BEEN ABANDONED. Supplanted BY THE SIMPLER SINGLE NEEDLE MEASURING 4, 6 OR 13 MM, TO BE USED ONCE ONLY. THE NEEDLE IS FASTENED INTO A SYRINGE WHOSE VOLUME VARIES BETWEEN 2 AND 10 CC. THIS MATERIAL CAN EITHER BE USED MANUALLY OR MOUNTED INTO AN ELECTRONIC OR MECHANICAL INJECTOR (DHN, PISTOR 3 OR 4, MESO SYSTEM).

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MESO-SYSTEM MESOTHERAPY GUN THIS GUN "MESO-SYSTEM" INTEGRATES THE MORE RECENT TECHNOLOGY APPLIED TO MESOTHERAPY. SPEED AND FREQUENCY OF THE INJECTION ARE CONTROLLED ELECTRONONICALLY. IT IS CONTROLLED BY MICRO-PROCESSOR AND WE HAVE 8 INJECTION PROGRAMS. Programmed PRESSION ADJUSTMENT OF THE SYRINGE, ELECTRONIC CONTROL OF DEPTH AND DOSE. RECHARGEABLE BATTERY INTEGRATED. Self-governance OF 6 HOURS IN CONTINUOUS USE. "MESO-SYSTEM" ACCEPTS ANY KIND OF SYRINGES AND NEEDLES. NO EXCLUSIVE KIT.

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SECURITY MEASURES BEFORE THE SESSION : THROUGH QUESTIONING TO DISCOVER ANY HISTORY OF ALLERGIES. Progressing TREATMENTS. Presence OF ACUTE OR CHRONIC PATHOLOGY. Against COAGULANT TREATMENT. THE PATIENT MUST STOP ANY TREATMENT WITH ASPIRIN OR ANTI-INFLAMMATORY MEDICATION TWO DAYS BEFORE THE PROCEDURE. AFTER THE SESSION : NO BATH OR SHOWER. NO CREAM AND HYDRATING MILK. Maintain a strategic distance from THE SUN FOR ONE DAY.

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MEDICATIONS IN MESOTHERAPY IN GENERAL, BETWEEN TWO AND FIVE DRUGS ARE MIXED AND INJECTED AT THE SAME TIME. THEIR CHEMICAL AND PHYSICAL COMPATIBILITY HAVE BEEN TESTED. IN THE BEGINNING, ALMOST ALL MEDICATIONS INJECTED INCLUDED PROCAÏNE . THIS PRODUCT WAS USED FOR ITS SYMPATHICOLYTIC AND VASO-DILATATION PROPERTIES. ITS USE, HOWEVER, WAS HIGHLY DEBATED DUE TO ITS HIGH ALLERGIC RISK BROUGHT BY PARAAMINOBENZOATE. IN FRANCE, PHYSICIANS PRATICING MESOTHERAPY HAVE NEVER ENCOUNTERED PROCAÏNE-LINKED ANAPHYLACTIC SHOCKS (THE MINIMUM DOSE INJECTED CAN NOT BE CONSIDERED AGGRESSIVE).

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DRUGS USED IN MESOTHERAPY MUST: BE APPROVED BY FRENCH DRUG AGENCY IN ORDER TO BE INJECTED. BE PACKAGED IN STERIL AMPULES. BE PREPARED JUST BEFORE THE SESSION.

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VASODILATORS DIHYDROERGOTAMINE (D.H.E.) PACKAGE : AMPULE OF 2 ML (1 mg) INDICATIONS IN USE OF MESOTHERAPY : MIGRAINES VENO-LYMPHATIC DEFICIENCY MESO INJECTION TECHNIQUE : IDS. CONTR A - INDICATION : PREGNANCY

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VASODILATORS ETAMSYLATE ( DYCINONE) PACKAGE : AMPULE OF 2 ML INDICATIONS IN USE OF MESOTHERAPY : LOCAL EDEMA AS VEINOTONIC. MESO INJECTION TECHNIQUES: IED, IDS, IDP, DHD. UNDESIRABLE EFFECTS : SKIN ALLERGY.

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PROCAINE BIOSTABILEX 2 % PACKAGE : AMPULE OF 5 ML (100 mg ) VALIDATE INDICATIONS : LOCAL ANESTHESIC INDICATIONS IN USE OF MESOTHERAPY : VASODILATOR ACTION CONTR A - INDICATIONS : EPILEPSY PROCAINE ALLERGY PREGNANCY UNDESIRABLE EFFECTS : EXCEPTIONNAL ALLERGY CARDIO-VASCULAR COLLAPSE CONVULSIONS CARDIAC ARYTHMIS

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LIDOCAINE (WITHOUT PARABEN CONSERVATOR ) : MESOCAINE PACKAGE : AMPULE OF 5 ML : 0.5 % AND 1 % (25 MG and 50 MG) INDICATIONS : LOCAL ANESTHESIC INDICATIONS IN USE OF MESOTHERAPY : VASODILATOR ACTION USE WHEN ALLERGIC SUSPICION RISK WITH PROCAINE UNDESIRALE EFFECTS : RARE ALLERGY

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VASODILATORS PRODUCTS BUFLOMEDIL (FONZYLANE) PACKAGE : AMPULE OF 5 ML (50 mg) INDICATIONS : PERIPHERAL VASODILATOR. MESO INJECTION TECHNIQUES: IED, IDS, IDP, DHD, NAPPAGE, PPP. CONTR A - INDICATION : EXCEPTIONNAL ALLERGY

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VASODILATORS PRODUCTS PENTOXIFYLLINE (TRENTAL) PACKAGE : AMPULE OF 5 ML (100 mg) INDICATIONS: PERIPHERAL VASODILATOR ANTI-FREE RADICALS ACTION. MESO INJECTION TECHNIQUES: IED, IDS, IDP, DHD, NAPPAGE, PPP. UNDESIRABLE EFFECT : SKIN ALLERGY

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VITAMINS VIT A, D3, E, B1, B2, PP, B6, VIT C (HYDROSOL POLYVITAMIN BON) PACKAGE : AMPULE OF 2 ML INDICATIONS IN USE OF MESOTHERAPY : ANTI FREE RADICALS ACTION. MESO INJECTION TECHNIQUES : IED, IDS, IDP, DHD. CONTRE-INDICATIONS : ALLERGY VIT. B1 HYPERCALCEMIA PREGNANCY

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CALCITONINE PHARMY II 50 UT and 100 UT PACKAGE : CIBACALCINE SALMON CALCITONIN (AMPULE OF 1 ML) INDICATIONS IN USE OF MESOTHERAPY : USED FOR ITS VASOMOTOR PROPERTIES LIKE ANTIOEDEMA AND VASO MODULATOR. MESOTHERAPY INJECTION TECHNIQUE : IED, IDS, IDP. CONTRE-INDICATIONS : ALLERGIC TO CALCITONINS. UNDESIRABLE EFFECTS : NAUSEA FLUSH ITCHING PARTICULAR OBSERVATIONS : UNDESIRABLE EFFECTS ARE MORE REDUCED IN MESOTHERAPY, WHEN USING IED AND IDS TECHNIQUES. SALMON CALCITONIN IS 25 TO 50 TIMES STRONGER THAN HUMAN CALCITONIN.

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VITAMIN C PACKAGE : LAROSCORBINE : AMPULES OF 5 ML VITAMIN C IS A POWERFULL ANTI-OXIDIZING AGENT. Hostile to Aging EFFECT OF VITAMIN C AND SYNTHESIS OF COLLAGEN TAKES PART IN SYNTHESIS OF ELASTIN. Secures VITAMIN An AGAINST OXIDATION. Ensures AGAINST SUN DAMAGE. EXEMPLE OF MIXTURE : VITAMIN C : 3 CC PROCAINE : 1 CC SALIN SERUM : 6 CC

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CONJONCTYL ( ORGANIC SILICIUM AND SALICYLIC ACID ) HAS BEEN RE-COMMERCIALED IN FRANCE SINCE JUNE 2004 PACKAGE : AMPULES OF 5 ML PROPERTIES : SILICIUM CONTROLS CELLULAR STIMULATION OF FIBROBLASTS AND PROMOTES THE REGENERATION OF COLLAGEN AND ELASTIN . Signs IN USE OF MESOTHERAPY : LIPOLYTIC ACTION TROPHIC ACTION : THE SKIN IS MORE FIRM, SOFT AND SMOOTH

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