Vicki Orzel RN/BSN MSN Understudy Alverno School Spring 2006.


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Pathophysiology of Gastro Esophageal Reflux Sickness Generally known as GERD Vicki Orzel RN/BSN MSN Understudy Alverno School Spring 2006 Clasp Craftsmanship got from Microsoft Office orzelva@alverno.edu
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Slide 1

Pathophysiology of Gastro Esophageal Reflux Disease Commonly known as GERD Vicki Orzel RN/BSN MSN Student Alverno College Spring 2006 Clip Art got from Microsoft Office orzelva@alverno.edu

Slide 2

** Click on the bolt at the base right to push ahead ** The bolt at the base left will take you back one and only slide ** Click on the gold catch in the middle, to take you back to the succession page, which like a table of contents**

Slide 3

Taking a Closer Look into GERD. Cut Art got from Microsoft Office

Slide 4

Sequence of learning instructional exercise, Click on one of the shapes for alternate route. STRESS RESPONSE BASIC ANATOMY WHAT GERD IS PHARMOCOGENOMICS GENETICS CELL GROWTH AND DEATH INFLAMMATION Acknowledgments SUMMARY

Slide 5

“Population based review uncovered that 44 % of the populace reported month to month indigestion and 19.8 % experienced acid reflux or corrosive disgorging in any event once a week”. (Zuckschwerdt, W. 2001) Clip Art got from Microsoft Office

Slide 6

“ GERD is more normal in whites contrasted and other ethnic gatherings. Be that as it may, the pervasiveness is expanding in Asians”. (Fennerty, 2003) It is additionally more regular in ladies, however men & individuals beyond 60 years old grow more difficulties. (Fennerty, 2003) Clip Art got from Microsoft Office

Slide 7

BASIC ANATOMY “The upper GI or gastro-intestinal tract comprises of the: Mouth Pharynx Esophagus Stomach The little & internal organs frame the lower GI tract”. (Porth, 1998 )

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The upper GI Tract is now and again alluded to as the Alimentary trench. (wikipedia) Clip Art got from Microsoft Office

Slide 9

Once any nourishment enters the mouth, it moves into the pharynx, which is the throat\'s back. (Porth,1998)

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Food is gone from the pharynx into the throat by an instrument called peristalsis. This impelling movement is completed by the muscles and the focal sensory system. (Porth, 1998)

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The nourishment is conveyed from the throat to the stomach where corrosive creation is shaped. (Porth,1998) Image with authorization from MDA Peristalsis proceeds in the throat.

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“The throat is exceptionally strong and breakdown when void. It is 10 inches or 25cm in length” (Porth, 1998)

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The throat is here and there alluded to as the “food tube” or the neck. It stretches out from the pharynx, which is the throat\'s back and experiences the diaphram to the stomach. Cut Art got from Microsoft Office

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The throat is back to (behind) the trachea Image with consent from Bristol-Meyers Squibb

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“The throat produces bicarbonate and mucus”. (Kahrilas, 2003) “The bicarbonate cradles the corrosive and bodily fluid framing a defensive barrier”. (Kahrilas, 2003) Clip Art got from Microsoft Office

Slide 16

This makes a situation in the throat of a higher pH than that of the stomach. The pH in the throat is ordinarily around 7-8, though the pH in the stomach is for the most part 2-4. (Kahrilas, 2003)

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pH remains for capability of hydrogen. Hydrogen is the thing that makes materials get to be acidic. 7 is viewed as impartial; anything under 7 is viewed as acidic. (Porth, 1998)

Slide 18

There are specific cells somewhere down in the stomach covering that influence the rate of corrosive generation. The essential cells which add to corrosive generation are known as parietal cells. (Kahrilas, 2003) Clip Art got from Microsoft Office

Slide 19

The coupling of these 3 receptors in the parietal cells starts the procedure of corrosive creation. (Kahrilas , 2003)

Slide 20

“The essential capacity of the actuated pumps are to : Each gastric parietal cell contains around 1 million corrosive pumps. Trade hydrogen particles from the parietal cells to potassium utilizing vitality got from part ATP.” (Kahrilas, 2003) Clip Art got from Microsoft Office

Slide 21

Ions trade at diverse rates taking into account the porousness of the parietal cells. The rate impacts the intracellular pH, bringing about a situation of sharpness or alkalinity of the stomach\'s phones. (Kahrilas, 2003)

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“The stomach delivers a normal of 2 liters of HCL a day, which in mix with the protein-part catalyst pepsin, separates chemicals in food”. (Kahrilas 2003) Clip Art got from Microsoft Office

Slide 23

There is an uncommon issue, called Zollinger-Ellison disorder: With this, the body delivers an extreme measure of corrosive, this can expand the danger of GERD. (CNN.com)

Slide 24

Upper It has a sphincter to keep air from entering the throat amid breaths. The sphincter for the most part opens for sustenance to pass. Lower It has a sphincter that opens while sustenance is being gone into the stomach. It is known as the LES, lower esophageal sphincter. The throat is isolated into: ( Porth, 1998)

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Click on True or False The neck is a stomach\'s piece.

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Sorry, You are wrong. The neck is another name for the throat . Cut Art got from Microsoft Office

Slide 27

Yes, you are right ! The neck is another name for the throat. Cut Art got from Microsoft Office

Slide 28

Click on True or False The throat is before the trachea.

Slide 29

Sorry, you are wrong. The throat is behind (back) the trachea. Picture with authorization from Bristol-Meyers Squibb. Cut Art got from Microsoft Office

Slide 30

Yes, you are right ! The throat is behind (back) the trachea Image with consent from Bristol-Meyers Squib. Cut Art got from Microsoft Office

Slide 31

Click on True or False The upper sphincter of the throat is in the upper GI & the lower sphincter is the lower GI.

Slide 32

Sorry, you are mistaken. The whole throat is in the upper GI. The upper GI tract comprises of the: mouth pharynx throat stomach The little & digestive organs frame the lower GI tract. Cut Art got from Microsoft Office

Slide 33

Yes, you are right! The whole throat is in the upper GI. The upper GI tract comprises of the: mouth pharynx throat stomach The little & internal organs shape the lower GI tract. Cut Art got from Microsoft Office

Slide 34

Click on True or False There are a million corrosive pumps in each gastric parietal cell.

Slide 35

Sorry, you are off base. There are 1 million corrosive pumps in each gastric parietal cell. Cut Art got from Microsoft Office

Slide 36

Yes, you are right! There are 1 million corrosive pumps in each gastric parietal cell. Cut Art got from Microsoft Office

Slide 37

What GERD is It is very much a perplexing process, I will probably streamline it for you. To start with, let’s separate it to the words it is comprised of: gastro = stomach esophogeal = sustenance tube reflux = reverse illness = anomalous state of physiologic working.

Slide 38

The Lower Esophageal Sphincter is The essential center identifying with GERD. Picture with authorization from Dr. Scott Tenner

Slide 39

If the Lower Esophageal Sphincter (LES) is not living up to expectations appropriately making a brokenness – the corrosive from the stomach can reverse into the throat. (Porth, 1998)

Slide 40

Images with consent from Life Enhancement

Slide 41

notwithstanding a brokenness of the lower esophageal sphincter (LES) Another variable is: Percentage of time the throat is presented to a low pH. Freedom of the corrosive relies on upon peristalsis & introduction to the salivation. (Porth, 1998)

Slide 42

Image with authorization from Healthy Living This uncomfortable feeling can now and then be mistaken for different conditions,

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