2020 PEDIATRIC SOFT TISSUE SARCOMA CONFERENCE AGENDA - PDF Document

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  1. 2020 PEDIATRIC SOFT TISSUE SARCOMA CONFERENCE AGENDA – DAY ONE Date: Thursday, February 6, 2020 7:30 AM – 5:00PM CDT Location: Pavilion for Women 4th Floor Conference Area Registration and Breakfast 7:30 – 8:00 Welcome Remarks Susan Blaney, MD Elise C. Young Chair of Pediatric Oncology, Baylor College of Medicine Director, Texas Children’s Cancer and Hematology Centers, Texas Children’s Hospital Introduction to Conference Wendy Allen-Rhoades, MD Director, Soft Tissue Sarcoma Program Assistant Professor, Baylor College of Medicine Session I: Molecular Pathology Moderator: Dolores Lopez-Terrada, MD, PhD Molecular and Genomic Diagnostic Approaches to Sarcoma Classification Angshumoy Roy, MBBS, PhD Associate Professor, Baylor College of Medicine Definition of Molecular Subgroups of Sarcoma Using FFPE RNA-seq Franck Tirode, PhD Cancer Research Center of Lyon, France Recent Discoveries in the Molecular Pathology of Rhabdomyosarcoma Jack Shern, MD Investigator, National Cancer Institute Germline Genetic Susceptibility to Rhabdomyosarcoma Philip Lupo, PhD Associate Professor, Baylor College of Medicine Question & Answer Coffee Break 8:00 – 8:05 8:05 – 8:15 8:15 – 8:35 8:35 – 8:55 8:55 – 9:15 9:15 – 9:35 9:35 – 9:45 9:45 – 10:00

  2. 2020 PEDIATRIC SOFT TISSUE SARCOMA CONFERENCE Session II: Basic and Translational Science Moderator: Jason Yustein, MD, PhD 10:00 – 10:15 Soft Tissue Sarcoma Models: Back to the Future Nino Rainusso, MD Assistant Professor, Baylor College of Medicine Dysregulated Notch and Hippo Signaling in RAS-driven Rhabdomyosarcoma Corinne Linardic, MD, PhD Associate Professor, Duke University The Role of p21 Activated Kinase in Rhabdomyosarcoma Jason Yustein, MD, PhD Associate Professor, Baylor College of Medicine Developmental Hijacking in Rhabdomyosarcoma Mark Hatley, MD, PhD Associate Member, St. Jude Children’s Research Hospital Targeting Metabolism in Rhabdomyosarcoma 10:15 – 10:35 10:35 – 10:55 10:55 – 11:15 11:15 – 11:30 Christine Heske, MD Assistant Clinical Investigator, National Cancer Institute New Approaches to Find Therapeutic Targets in Rhabdomyosarcoma Stephen Skapek, MD Professor, UT Southwestern Medical Center Question & Answer Lunch and Networking Session 11:30 - 11:50 11:50 – 12:00 12:00 – 1:00 Session III: Non-Rhabdomyosarcoma Soft Tissue Sarcomas Moderator: Fatih Okcu, MD Treatment Challenges of NRSTS: The European Experience Andrea Ferrari, MD Istituto Nazionale Tumori, Milano Itali Preoperative Chemoradiation with Pazopanib in NRSTS: A Successful Collaboration Between Pediatric and Adult Consortia Aaron Weiss, DO Assistant Professor, Maine Medical Center 1:00 – 1:25 1:25 – 1:50

  3. 2020 PEDIATRIC SOFT TISSUE SARCOMA CONFERENCE 1:50 – 2:15 Clinical Updates for Pediatric Desmoid Tumors Daniel Orbach, MD Institut Curie – Paris, France Recent Findings from the Children’s Oncology Group NRSTS Study ARST0332 Sheri Spunt, MD Professor, Stanford University Question & Answer Coffee Break 2:15 – 2:40 2:40 – 2:50 2:50- 3:00 Session IV: Rhabdomyosarcoma Moderator: Douglas Harrison, MD 3:00 – 3:25 History of Rhabdomyosarcoma: From the Stone Age to the Age of Discovery Or Carrying Coals to Newcastle Carola Arndt, MD Professor, Mayo Clinic The Past, Present, and Future of Maintenance Chemotherapy in Rhabdomyosarcoma Douglas Hawkins, MD Professor, University of WashingtonSchool of Medicine Value of Surveillance Imaging in Rhabdomyosarcoma Stephanie Fetzko, MD Instructor, Baylor College of Medicine Infant Spindle Cell Rhabdomyosarcoma Sarah Whittle, MD Assistant Professor, Baylor College of Medicine Trial Development for High Risk Rhabdomyosarcoma Wendy Allen-Rhoades, MD Assistant Professor, Baylor College of Medicine Question and Answer/Closing 3:25 – 3:50 3:50 – 4:05 4:05 – 4:20 4:20 – 4:45 4:45 – 5:00

  4. 2020 PEDIATRIC SOFT TISSUE SARCOMA CONFERENCE AGENDA – DAY TWO Date: Friday, February 7, 2020 7:30 AM – 1:00 PM CDT Location: Pavilion for Women 4th Floor Conference Area 7:30 – 8:00 Breakfast 8:00 – 8:10 Day 2 Overview Wendy Allen-Rhoades, MD Assistant Professor, Baylor College of Medicine 8:10 – 08:30 Session V: Patient and Family Session Steven and Melissa Batchelder Session VI: Abstract Winners Moderator: Wendy Allen-Rhoades, MD The Oncogenic Role of Hedgehog Pathway Co-Receptors in Rhabdomyosarcoma: Expanding Knowledge to Discover New Therapeutic Targets Josep Roma, PhD Vall d'Hebron Research Institute, Barcelona, Spain Development of Immune-Based Therapies for the Treatment of Pediatric Rhabdomyosarcoma Fabrice Lucien, PhD Associate Consultant, Mayo Clinic Approach to Head and Neck Sarcomas: A Single Institution Experience Anthony Sheyn, MD Assistant Professor, University of Tennessee Health Science Center Primary Intracranial Sarcoma with DICER1 Mutation: Treatment Results of a Novel Molecular Entity Rosdali Díaz Coronado, MD National Institute of Neoplastic Diseases, Lima, Peru 8:30 – 8:40 8:40– 8:50 8:50 – 9:00 9:00 – 09:10

  5. 2020 PEDIATRIC SOFT TISSUE SARCOMA CONFERENCE Session VII: Local Control Moderator: Sanjeev Vasudevan, MD 9:10 –9:30 Current Issues in Radiation Therapy for NRSTS Stephanie Terezakis, MD Professor, University of Minnesota Team Sports: Advancing Quality in Pediatric Head and Neck Tumor Care Daniel Chelius, MD Assistant Professor, Baylor College of Medicine Lymph Node Assessment in Soft Tissue Sarcoma Roshni Dasgupta, MD Professor, University of Cincinnati Surgical Local Control for Abdominal Metastatic Soft Tissue Sarcoma Andrea Hayes-Jordan, MD Professor, University of North Carolina Question and Answer (Sessions VI and VII) 09:30 – 9:50 9:50 – 10:10 10:10 – 10:30 10:30 –10:45 10:45 – 11:00 Coffee Break Session VIII: New Therapies Moderator: Wendy Allen-Rhoades, MD 11:00 – 11:20 Maximizing the Model - The Preclinical Pediatric Sarcoma Experience Elizabeth Stewart, MD Assistant Member, St. Jude Children’s Research Hospital Basic Science to Clinical Trial: Entinostat to Turn Off PAX3:FOXO1 Charles Keller, MD Children’s Cancer Therapy Development Institute Chimeric Antigen Receptor T cells for Rhabdomyosarcoma Meena Hegde, MBBS Assistant Professor, Baylor College of Medicine Modified NK Cell Therapy for Soft Tissue Sarcomas Robin Parihar, MD, PhD Assistant Professor, Baylor College of Medicine 11:20 – 11:40 11:40 – 12:00 12:00 – 12:20

  6. 2020 PEDIATRIC SOFT TISSUE SARCOMA CONFERENCE 12:20 – 12:45 The Promise and Challenge of Molecular Targeted Therapy for Pediatric Sarcomas Leo Mascarenhas, MD, MS Associate Professor, Children’s Hospital of Los Angeles Question & Answer 12:45 – 1:00 1:00 - 2:00 Lunch and Closing Remarks