Biomet Inc. and its Subsidiaries' Trademarks

1. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Conception et validation dune instrumentation usage unique pour la pose dune prothse de hanche Muriel Benedetto Marmilloud Biomet France

2. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Lide Dvelopper une instrumentation complte usage unique pour larthroplastie de la hanche. Remplacer intgralement lutilisation dun ancillaire mtallique.

3. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Cahier des charges

4. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Exigences gnrales Bio-compatibilit Rsistance la strilisation Gamma et vapeur Possibilit dobtention dtat de surface lisse vitant la rtention de polluants Grande tnacit pour viter les bris dinstruments et risques dabandon de dbris dans le patient Stabilit fonctionnelle : conserver dans le temps laspect, la morphologie, les proprits dusage

5. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Exigences particulires La fonction de linstrument dtermine des exigences mcaniques particulires : Rpe : rsistance l usure (viter les dbris), grande qualit de coupe ou rsistance labrasion, aux dformations et aux risques de rupture, malgr une gomtrie parfois complexe Impacteurs: rsistance aux chocs, au matage Autres : rsistance la dformation , au matage

6. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. La rponse du matriau 2U Composition renforce base de polyarylamide Trs haute rigidit Module dlasticit > 23GPa Forte rsistance aux contraintes mcaniques Rsistance en flexion peut atteindre 400 Mpa Facilit de mise en uvre, galement en parois minces et formes complexes Faible retrait au moulage, trs reproductible Excellent fini de surface Trs rsistant aux rayons Gamma et la strilisation vapeur

7. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. 1 re tape : validation du concept Moule dinjection Rpes plastiques

8. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Essais au laboratoire danatomie 1 re tape : validation du concept

9. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Tests biologiques et mcaniques marquage CE Etude conomique Etude de march Environ 50 chirurgies ont t ralises avec succs. Excellent retour des chirurgiens et du personnel hospitalier 1 re tape : validation du concept

10. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Design dfinitif des instruments Impacteur de tte Impacteur de tige 2me tape : Finalisation

11. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Injection

12. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. En salle blanche

13. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Essais et validations Caractrisation physico-chimique complte Essais mcaniques Analyses de biocompatibilit Incidence de la strilisation et stabilit dans le temps Validations : Injection Nettoyage final Conditionnement Strilisation Gamma

14. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Essais mcaniques Essai de flexion 3 points sur banc dessai sur Rpes injectes, strilises Gamma et strilises vapeur : -5% entre les deux modes de strilisation et les pices d'origine mais Gamma > vapeur Contrle de routine rception des pices injectes

15. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Essais mcaniques Essais sur fmur en rsine : la rpe casse avant le fmur ou lon relve une contrainte maximum de Von Mises de 62MPa

16. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Essais fonctionnels sur rpe Prsences de zones dabrasion Parfois quelques traces de perte matire Perte en masse non mesurable

17. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Biocompatibilit Matriau sans antcdent pour une application similaire Donnes toxicologiques limites Caractrisation chimique fournie par le fabricant insuffisante Or, Polymre, type considr comme risque les rpes sont en contact direct avec los, mais aussi le sang hypothse : possible casse ou relargage de dbris => contact permanent Batterie complte de tests de biocompatibilit selon ISO 10993-1 Prise en compte de coefficients de scurit maximums

18. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Biocompatibilit Cytotoxicit NF EN ISO 10993-5 Toxicit systmique aigue NF EN ISO 10993-11 Test dirritation cutane NF EN ISO 10993-10 Test maximalis de sensibilisation NF EN ISO 10993-10 Hmolyse NF EN ISO 10993-4 Gnotoxicit : test dAMES NF EN ISO 10993-3 Toxicit subchronique par implantation sous-cutane - 28 jours Essai dimplantation NF EN ISO 10993-6 Caractrisation physico-chimique complte ISO 10993-18 & -19

19. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Simulation de transport, Simulation de stockage en conditions extrmes Test de maintien de la strilit Test de maintien de la prsentation aseptique Tests de performance

20. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Rpes avec manche ergonomique Tailles 1 9 gauche et droit Impacteur de tte Impacteur de tige Exception Tiges dessai Ttes dessai Matriel

21. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. Les prochaines tapes Etude environnementale en cours Comparaison ancillaire 2U et traditionnel Analyse du cycle de vie Bio Intelligence service Travail sur le conditionnement des instruments Ergonomie Design Image

22. (Product Name) is a/are trademark(s) of Biomet Inc. or its subsidiaries. All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless indicated otherwise. MERCI POUR VOTRE ATTENTION